Holding(s) in Company

Holding(s) in Company

Holding(s) in Company

Holding(s) in Company


Released: 11/01/2011

TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESi

1. Identity of the issuer or the underlying issuer

Biocompatibles

of existing shares to which voting rights are International plc attached:ii

2 Reason for the notification (please tick the appropriate box or boxes): An acquisition or disposal of voting rights √

An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments An event changing the breakdown of voting rights

Other (please specify): 3. Full name of person(s) subject to the Deutsche Bank AG notification obligation:iii

4. Full name of shareholder(s)

(if different from 3.):iv

5. Date of the transaction and date on which the threshold is crossed or

07/01/2011 reached: v

6. Date on which issuer notified:

10/01/2011

7. Threshold(s) that is/are crossed or

4% reached: vi, vii 8. Notified details:

A: Voting rights attached to shares viii, ix Class/type Situation previous Resulting situation after the triggering transaction of to the triggering shares transaction if possible Number Number Number Number of voting % of voting rights using of of of shares rights x the ISIN Shares Voting CODE Rights Direct Direct xi Indirect xii Direct Indirect GB00B0L2JD04 1,217,815 1,217,815 1,617,815 1,617,815 n/a 4.11% n/a

B: Qualifying Financial Instruments Resulting situation after the triggering transaction

Type of Expiration Exercise/ Number of voting % of voting financial date xiii Conversion Period xiv rights that may be rights instrument acquired if the instrument is exercised/ converted. C: Financial Instruments with similar economic effect to Qualifying Financial Instruments xv, xvi

Resulting situation after the triggering transaction Type of Exercise price Expiration Exercise/ Number of voting rights % of voting financial date xvii Conversion instrument refers to rights xix, xx instrument period xviii Nominal Delta Total (A+B+C) Number of voting rights Percentage of voting rights 1,617,815 4.11%

9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable: xxi

Proxy Voting: 10. Name of the proxy holder:

11. Number of voting rights proxy holder will cease

to hold:

12. Date on which proxy holder will cease to hold

voting rights: 13. Additional information: 14. Contact name: Dirk Young 15. Contact telephone number:

+44(20)754-57177

vendor

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